Fortschritte der Arzneimittelforschung  v. 30 ~ v. 50

hrsg. von Ernest Jucker

Founded in 1959, this series encompasses all fields concerned with the development of new therapeutic drugs and the elucidation of their mechanisms of action, reflecting the increasingly complex nature of modern drug research. Invited authors present their biological, chemical, biochemical, physiological, immunological, pharmaceutical, toxilogical, pharmacological and clinical expertise in written reviews and provide the newcomer and the specialist alike with an up-to-date list of references. This volume contains six reviews by recognized experts. They offer the reader information on: developments in research on histamine (H1) receptor agonists; antifungal chemotherapy; the diversity of heterocyclic compounds and their biological activities; newer antifolate compounds in cancer therapy; non-steroidal agents for regulation of the menstrual cycle; and developments in anti-convulsant drugs.

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From the contents: A- C. Brater and M. D. Murray: The effects of NSAIDs on the kidney A- G. Edwards and A. H. Weston: Latest developments in potassium channel modulator drugs A- M.R. Juchau and Y. Huang: Chemical teratogenesis in humans: Biochemical and molecular mechanisms A- S.P. Gupta: Studies on cardiovascular drugs A- G. Polak: Antifungal chemotherapy: An everlasting battle A- O. Valdenaire: New insights into the bioamine receptor family

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Progress in Drug Research is a prestigious book series (founded in 1959) which provides extensive expert-written reviews on a wide spectrum of highly topical areas in current pharmaceutical and pharmalogical research. Each volume contains fully cross-referencing indexes which link the volumes together, forming a virtually encyclopaedic work. The series thus serves as an important, time-saving source of information for researchers concerned with drug research and all those who need to keep abreast of the many recent developments in the quest for new and better medicines.<p>Volume 50 in the series includes: <p>P.N. Kaul: Drug discovery: Past, present and future<p>M. Rohmer: Isoprenoid biosynthesis via the mevalonate -- independent route, a novel target for antibacterial drugs<p>G. Edwards and A.H. Weston: Endothelium, -derived hyperpolarizing factor -- a critical appraisal<p>R.W. Rockhold: Glutamatic involvement in psychomotor stimulant action<p>J.M. Colacino and K.A. Staschke: The identification and development of antiviral agents for the treatment of chronic hepatitis B virus infection<p>T.D. Johnson: Polyamines and cerebral ischemia

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This is Volume 42 in a series featuring reviews on a wide spectum of topical areas in current pharmaceutical and pharmacological research. Founded in 1959, the series has moved from its initial focus on medicinal chemistry to a much wider scope. Today, it aims to encompass all fields concerned with the development of new therapeutic drugs and the elucidation of their mechanisms of action, reflecting the increasingly complex nature of modern drug research. Invited authors present their biological, chemical, biochemical, physiological, immunological, pharmaceutical, toxicological, pharmacological and clinical expertise in written reviews, providing the newcomer and specialist alike with an up-to-date list of prime references. Each volume of "Progress in Drug Research" contains fully cross-referencing indexes which link the books together.

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This series provides expert-written reviews on a wide spectrum of topical areas in pharmacological and pharmaceutical research. It encompasses all fields concerned with the development of new therapeutic drugs and the elucidation of their mechanisms of action, reflecting the increasingly complex nature of modern drug research. Each volume is cross-referenced to the others in the series. Topics covered in this volume include: cholesterol-lowering drugs and drugs for other metabolic disorders involving lipids; the progress achieved since the 1940s in the search for ideal antihypertensive drugs; natural polyamines and their role in the immune system; biologically active quinazolones, a class of chemically related substances with a wide range of different effects; and recent advances in research on gene regulation and expression of interferons.

「Nielsen BookData」より

This series was founded in 1959, and its focus has shifted from medicinal chemistry to a much wider scope. It now encompasses all fields concerned with the development of therapeutic drugs and the elucidation of their mechanisms of action, reflecting the increasingly complex nature of modern drugs research. Invited authors write reviews on the following fields: biology, chemistry, biochemistry, physiology, immunology, pharmacy, toxicology, pharmacology, and clinical aspects. The books are linked by indexes in each volume, forming an almost encyclopaedic work.

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This text is part of a series which encompasses all fields concerned with the development of new therapeutic drugs and the elucidation of the mechanisms of action, reflecting the increasingly complex nature of modern drug research. In this collection, papers discuss biological, chemical, biochemical, physiological, immunological, pharmaceutical, toxicological, pharmacological and clinical areas in an attempt to keep abreast of the many developments in the quest for new and better medicines.

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Volume 46 of this well-established and acclaimed book series contains seven comprehensive reviews by internationally recognized experts. They will provide the reader with up-to-date information. Contents: N.K. Hollenberg and S.W. Graves: Endogenous sodium pump inhibition: Current Status a [ R.B. McCall: Neurotransmitters involved in the central regulation of the cardivascular system a [ W.T. Jackson and J.H. Fleisch: Development of novel anti- inflammatory agents: A pharmacologic perspective on leukotrienes and their receptors a [ M. Margaglione, E. Grandone, F.P. Mancini and G. Di Minno: Drugs affecting plasma fibrinogen levels. Implications for new antithrombotic strategies a [ N. Seiler, A. Hardy and J.P. Moulinoux: Aminoglycosides and polyamines: Targets and effects in the mammalian organism of two important groups of natural aliphatic polycations a [ J. Claghorn and M.D. Lesem: Recent developments in antidepressant agents a [ E.J. Lien, A. Das and L.L. Lien: Immunopharmacological and biochemical bases of Chinese herbal medicine a [ Index Vol. 46 a [ Index of titles Vols. 1-46 a [ Author and paper index Vols. 1-46

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The Series Progress in Drug Research was founded by its current editor in 1959 for the purpose of providing review articles on topical areas of pharmaceutical research. In the beginning, during the "Golden Age" of drug discoveries, these surveys were chiefly focused on chemical pharmacological and preclinical investigations. Gradually, the search for new medicines c increasingly complex as new disciplines entered the research arena augmenting or even partly replacing the traditional research. fields. The more recent volumes of Progress m Drug Research contain mainly review articles on biochemical, biological, immunological, physiological Clinical and medicinal of drug research. The Contents of the recent volumes demonstrate the complex nature of today's search for new medicines. The 40 volumes of Progress in Drug Research so far available contain over 440 review articles, innumerable references to original publications, as well as extensive indexes. Researchers who are actively engaged in the various scientific branches of drug research will be greatly assisted in their own work by the comprehensive surveys and will certainly profit from the vast experience of the respective authors. Those who want to keep abreast of new developments in this area, without the burden of reading innumerable original papers, will certainly appreciate the almost encyclopedic nature of this series.

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[目次]

  • Drug discovery - past, present and future, P.N. Kaul
  • isoprenoid biosynthesis via the mevalonate-independent route, a novel target for antibacterial drugs?, M. Rohner
  • endothelium-derived hyperpolarizing factor - a critical appraisal, G. Edwards and A.H. Weston
  • glutamatic involvement in psychomotor stimulant action, R.W. Rockhold
  • the identification and development of antiviral agents for the treatment of chronic hepatitis B virus infection, J.M. Colacino and K.A. Staschke
  • polyamines and cerebal ischemia, T.D. Johnson.

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[目次]

  • Drugs for treatment of patients with high cholesterol blood levels and other dyslipidemias, Harold E. Bays and Carlos Dujovne
  • in search of ideal antihypertensive drugs - progress in five decades, Eric J. Lien, Hua Gao and Linda L. Lien
  • the natural polyamines and the immune system, N. Seiler and C.L. Atanassov
  • biologically active quinazolones, Shradha Sinha and Mukta Srivastava
  • production and action of interferons - new insights into molecular mechanisms of gene regulation and expression, Mark P. Hayes and Kathryn C. Zoon
  • addendum to "Natural products as anti-cancer agents", Shrada Sinha and Sudha Jain.

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[目次]

  • R. Sutherland Bacterial resistance to B-lactam antibiotics: problems and solutions J W. Fischer Recent advances in erythropoietin research H Ohtaka and T Fujita Strutural modification patterns from agonists to antagonists and their application to drug design - A new serotonin (5-HT3) antagonist series S. Batra, M Seth, and A. P. Bhaduri Chirality and future drug design M R Juchau Chemical teratogenesis P, J Walker and J P. Fawcett Drug nephrotoxicity - The significance of cellular mechanisms .

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[目次]

  • * Inhalt * Sommaire.- Leukotriene antagonists and inhibitors of leukotriene biosynthesis as potential therapeutic agents.- Bacterial resistance to antibiotics: The role of biofilms.- Pharmacological properties of the natural polyamines and their depletion by biosynthesis inhibitors as a therapeutic approach.- Potassium channel openers: Airway pharmacology and clinical possibilities in asthma.- Antifungal chemotherapy: Are we winning?.- The hopanoids, bacterial triterpenoids, and the biosynthesis of isoprenic units in prokaryotes.- Isosterism and bioisosterism in drug design.- Index * Sachverzeichnis * Table des matieres, Vol. 37.- Index of titles * Verzeichnis der Titel * Index des titres * Vol. 1-37.- Author and paper index * Autoren- und Artikelindex * Index des auteurs et des articles, Vol. 1-37.

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この本の情報

書名 Fortschritte der Arzneimittelforschung
著作者等 Allison Anthony C.
Antonaccio Michael J.
Di Minno G.
Fudenberg H.Hugh
Fuller Ray W.
Jucker Ernst
Lee W. Simon
Lien Eric J.
McCall Robert B.
Oehman L.
Pfaltz C.R.
Russell Roger Wolcott
Salzman C.
Saxena Anil K.
Schultz Richard M.
Sharma Satyavan
Silver Melvin J.
Singh Vijendra K.
Sinha Shradha
Solomon David A.
Warburton David M.
Webb David R.
Jucker Ernest
巻冊次 v. 30
v. 31
v. 32
v. 33
v. 34
v. 35
v. 36
v. 37
v. 38
v. 39
v. 40
v. 41
v. 42
v. 43
v. 44
v. 45
v. 46
v. 47
v. 48
v. 49
v. 50
出版元 Birkhäuser
刊行年月 1960-
ページ数 v.
大きさ 25 cm
ISBN 3764318376
3764319437
376432306X
3764323515
3764324996
3764325828
3764326263
3764327057
3764327170
3764328509
3764329254
3764329955
3764350423
3764351497
3764352124
3764352981
376435299X
3764356715
3764356723
3764358211
3764317523
NCID BA08662035
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言語 ドイツ語
出版国 スイス
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